A Manchester United XI will play at crisis club Luton Town in a pre-season friendly on Tuesday July 28, kick of 19:45.
Luton were relegated to the Blue Square North League last season after being docked 30 points due to financial problems.
Club staff want to develop their youth development department and the reds have agreed to play the match to help them raise funds.
United haven't played at Kenilworth Road since 1995.
Ticket details will be released later this month.